I have a 23 in monitor and still have the problem. What would be considered a low resolution?
This is the only site I have a problem with (since the overnight changes)
Wow, really? Then you most likely have, as someone suggested, a very
low screen resolution setting, maybe 800 x 600. Do you vision problems, perhaps? In XP, Vista, and W7, you can access the video display settings by right-clicking on your desktop and following the menus. You should be able to get 1680 x 1050 or thereabouts, depending on your CPU. If you have an older computer, it may not be powerful enough on the video end to support a decent resolution on a large monitor.
On the other hand, you say this is the only site you have a problem with... have you tried the zoom-out keyboard shortcut mentioned? Hold down CTRL and press the minus key ( - ) up beside the + key.